Serum Immune Proteins in Limb Lymphedema Reflecting Tissue Processes Caused by Lymph Stasis and Chronic Dermatolymphangioadenitis (Cellulitis).
Identifieur interne : 000188 ( Main/Exploration ); précédent : 000187; suivant : 000189Serum Immune Proteins in Limb Lymphedema Reflecting Tissue Processes Caused by Lymph Stasis and Chronic Dermatolymphangioadenitis (Cellulitis).
Auteurs : Marzanna T. Zaleska [Pologne] ; Waldemar L. Olszewski [Pologne]Source :
- Lymphatic research and biology [ 1557-8585 ] ; 2017.
Abstract
Lymphedema of limbs affects a large mass of tissues. Pathological changes develop in skin and subcutaneous tissue. Bacterial retention in edema fluid is followed by chronic inflammatory reaction. The question arises whether the chronic processes affecting a large mass of limb tissues are reflected in the serum by appearance of specific proteins accumulating and subsequently absorbed from the lymphedematous tissues Aim: To measure the concentration of serum proteins (1) participating in cellular disintegration such as caspase 1, sFas, high-mobility group box 1 (HMGB1), and serpin, (2) cell growth regulating factors such as cortisol, human growth hormone, keratinocyte growth factor, and insulin-like growth factor (IGF), and (3) angiogenic and growth factors such as angiopoetins 1 and 2, adiponectin, leptin, and transforming growth factor beta.
DOI: 10.1089/lrb.2017.0003
PubMed: 28880710
Affiliations:
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Zaleska</name><affiliation wicri:level="1"><nlm:affiliation>1 Department of Applied Physiology, Mossakowski Medical Research Center , Warsaw, Poland .</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>1 Department of Applied Physiology, Mossakowski Medical Research Center , Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Olszewski, Waldemar L" sort="Olszewski, Waldemar L" uniqKey="Olszewski W" first="Waldemar L" last="Olszewski">Waldemar L. Olszewski</name><affiliation wicri:level="1"><nlm:affiliation>2 Department of Vascular Surgery, Central Clinical Hospital , Ministry of Home Affairs, Warsaw, Poland .</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>2 Department of Vascular Surgery, Central Clinical Hospital , Ministry of Home Affairs, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author></analytic><series><title level="j">Lymphatic research and biology</title><idno type="eISSN">1557-8585</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphedema of limbs affects a large mass of tissues. Pathological changes develop in skin and subcutaneous tissue. Bacterial retention in edema fluid is followed by chronic inflammatory reaction. The question arises whether the chronic processes affecting a large mass of limb tissues are reflected in the serum by appearance of specific proteins accumulating and subsequently absorbed from the lymphedematous tissues Aim: To measure the concentration of serum proteins (1) participating in cellular disintegration such as caspase 1, sFas, high-mobility group box 1 (HMGB1), and serpin, (2) cell growth regulating factors such as cortisol, human growth hormone, keratinocyte growth factor, and insulin-like growth factor (IGF), and (3) angiogenic and growth factors such as angiopoetins 1 and 2, adiponectin, leptin, and transforming growth factor beta.</div></front></TEI><affiliations><list><country><li>Pologne</li></country></list><tree><country name="Pologne"><noRegion><name sortKey="Zaleska, Marzanna T" sort="Zaleska, Marzanna T" uniqKey="Zaleska M" first="Marzanna T" last="Zaleska">Marzanna T. Zaleska</name></noRegion><name sortKey="Olszewski, Waldemar L" sort="Olszewski, Waldemar L" uniqKey="Olszewski W" first="Waldemar L" last="Olszewski">Waldemar L. Olszewski</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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